Vitamin B6 (Pyridoxine)

Vitamin B6, also known as pyridoxine, is a member of the water soluble B vitamin family. A composite of three related chemicals, pyridoxine, pyridoxal, and pyridoxamine, it acts as a cofactor for many enzymes that catalyse the breakdown of amino acids. Pyridoxine is widely distributed in foods, with liver, chicken, fish, pork, milk, eggs, whole grains, potatoes, beans, nuts, seeds, and green leafy vegetables all good sources. 

Functions

Functions:

Vitamin B6 assists many functions in the body namely:

  • Assists in the formation of several neurotransmitters, chemicals that carry signals from one nerve cell to another.
  • Assisting normal brain development and function.
  • Assisting the production of the hormones serotonin and norepinephrine, which influences mood and melatonin which helps to regulate the body clock.
  • Helping to convert food (carbohydrates) into fuel (glucose) which is used to produce energy.
  • Helping to metabolise fats and protein.
  • To help product great, skin, hair, eyes and liver.
  • To break down protein
  • To keep blood sugar with in recommended ranges
  • To help make harmoglobin.

Reference Intake (RI)

    AGE

   CHILDREN

    MALES

FEMALES

MALES

FEMALES

PREGNANCY

  YEARS

1-3

4-6

7-10

11-14

15-17

11-14

15-17

18-64

65+

18-64

65+

 

VITAMIN B6 (µg / g protein)

15

15

15

15

15

15

15

15

15

15

15

       (No increment)

 

    MONTHS

0-3

4-6

7-9

10-12

LACTATION

VITAMIN B6 (µg / g protein)

8

8

10

13

       (No increment)

Food Sources

PRODUCTS

Sunflower Seeds

Pistachio Nuts

Tuna (cooked)

Turkey (cooked)

(µg / 100 g)

1.35

1.12 

1.04

0.81 

PRODUCTS

Prunes

Lean Beef (cooked)

 Banana

Avocado

(µg / 100 g) 

0.75

   0.68 

0.37 

0.29

 

Deficiency / Toxicity

Although vitamin B6 is found in a variety of foods, deficiency may arise as a result of high dietary protein intake (80 - 160 g / d). Signs of clinical deficiency may include the following;

  • Water retention
  • Tingling Hands 
  • Depression or nervousness
  • Irritability
  • Muscle cramps
  • Lack of energy
  • Flaky skin


Whilst vitamin B6 toxicity is rare, studies in which subjects injested high-dose (50 - 500 mg / d, and 2 - 7 g / d) pyridoxdine reported development of peripheral sensory neuropathy (damage to nerves leading to reduced sensitivity to touch, temperature, pain and impaired balance and co-ordination). In all cases, symptoms resolved after withdrawal of supplementation.